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Updated: Jun 26, 2025

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
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内源性逆转录病毒调节免疫转录调节器SP140的瘤特异性表达

Adam K Dziulko1, Holly Allen1, Edward B Chuong1

  • 1Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, JSC Biotech Bldg, Boulder, Colorado 80303, USA.

Human molecular genetics
|May 16, 2024
PubMed
概括

斑点蛋白140 (SP140) 通常存在于免疫细胞中,但我们在癌症中发现了它. 这种特定于癌症的SP140表达是由内源逆转录病毒 (ERV) 驱动的,并影响免疫基因调节.

关键词:
癌症 癌症 癌症 癌症内源性逆转录病毒是一种内源性逆转录病毒豁免权是一种豁免权.SP140 SP140 是一个很好的标签.

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