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Updated: Jun 26, 2025

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拷贝数变异和对智力的多基因风险会给自闭症谱系障碍带来风险,无论它们对认知能力的影响如何

Zoe Schmilovich1,2,3, Vincent-Raphaël Bourque3,4, Elise Douard3,4

  • 1Department of Human Genetics, McGill University, Montréal, QC, Canada.

Frontiers in psychiatry
|May 16, 2024
PubMed
概括

罕见的副本数变异 (CNVs) 和对智力的多基因风险 (PRS-IQ) 增加自闭症谱系障碍 (ASD) 风险,无论它们对认知能力的影响如何. 这些遗传因素似乎通过不同的途径影响ASD易感性和认知功能.

关键词:
ASD 自闭症谱系障碍 自闭症谱系障碍CNV (复制号变种) 是指复制号的变种.认知能力 认知能力智力指数 (IQ) 是指智力指数.多基因风险评分 (PRS)

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