结膜状细胞癌的眼内侵袭:临床表现,组织病理学发现和结果
Ysé Borella1, Livia Lumbroso1, Christine Lévy1
1Department of Ocular Oncology, Institut Curie, Paris, France.
Ocular oncology and pathology
|May 16, 2024
概括
结膜状细胞癌 (SCC) 的眼内侵袭是罕见但严重的. 早期检测和三级中心的专业治疗对于管理这种侵略性的眼瘤至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 结膜状细胞癌 (SCC) 可以侵入膜或角膜,导致眼内局部化.
- 眼内入侵是一种罕见但显著的结膜SCC的并发症.
研究的目的:
- 描述结膜SCC与眼内侵袭的临床和病理学发现.
- 从文献和目前的案例系列中审查此类案件的管理和结果.
主要方法:
- 4名患者的临床特征,组织病理学,管理和随访数据的回顾性分析.
- 在过去的30年里,结膜SCC与眼内侵袭的文献综述.
主要成果:
- 两名患者出现了初级眼内侵入;两名患者在先前治疗后出现了复发.
- 所有患者都有结膜手术的病史,但没有眼内手术.
- 治疗包括修改的核化或轨道化,其中一些需要辅助放射治疗.
- 组织病理学在所有病例中都发现了差异很好的结膜SCC,在随访时没有远程转移.
结论:
- 结膜SCC的眼内侵袭是一种不常见但具有挑战性的并发症.
- 管理需要在第三级中心提供专门的护理,并进行长期的随访.
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