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Updated: Jun 26, 2025

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
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在遗传性帕金森病中的外围皮肤同核蛋白病变特征

Yanpeng Yuan1,2,3, Yangyang Wang1,2,3, Minglei Liu1

  • 1Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

Frontiers in neurology
|May 16, 2024
PubMed
概括

皮肤酸化α-synuclein (p-α-syn) 沉积是帕金森病 (PD) 的生物标志物. 这项研究在遗传性PD患者中发现了p-α-syn,这表明皮肤活检可以诊断PD并反映大脑病理.

关键词:
CHCHD2是指CHCHD2的两个部分.在RAB39B中,可以使用RAB39B.这就是SAAA.遗传性帕金森氏症是一种疾病.皮肤活检皮肤活检α-synuclein 是一种同核蛋白.

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