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运动训练对肌肉交感神经活动的影响:系统性审查和元分析
Sarah E Meyer1, Miranda Kimber1, Lauren E Maier1
1Neurovascular Health Laboratory, Program for Pregnancy and Postpartum Health, Women and Children's Health Research Institute, Alberta Diabetes Institute, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|May 16, 2024
概括
运动训练显著降低了肌肉交感神经活动 (MSNA),有利于心血管健康. 这种效应在心血管疾病患者中更为明显,显示了与干预前活动水平的剂量反应关系.
科学领域:
- 运动生理学 运动生理学
- 心血管健康 心血管健康
- 自主神经系统的调节规则
背景情况:
- 肌肉交感神经活动 (MSNA) 在调节心血管功能方面发挥着至关重要的作用.
- 增加的MSNA与各种心血管疾病有关.
- 了解运动对MSNA的影响对于开发非药物干预措施至关重要.
研究的目的:
- 系统地审查和元分析运动训练对人类MSNA的影响.
- 评估运动干预后MSNA,心率,血压和有氧能力的变化.
- 调查心血管疾病和没有心血管疾病的个体之间MSNA反应的潜在差异.
主要方法:
- 40项干预研究的系统审查和元分析 (n=1,253).
- 包括随机对照试验 (RCT),非RCT和前后干预研究.
- 通过微神经图直接评估MSNA;结果包括MSNA指标,心率,血压和有氧能力.
主要成果:
- 与对照组相比,运动训练显著降低了MSNA爆发频率和发生率.
- 患有心血管疾病的人群中,MSNA爆发发病率的减少比没有心血管疾病的人群中更大.
- 后回归显示了一种剂量-反应关系:更高的干预前MSNA预测了更大的干预后减少.
结论:
- 运动训练有效地减少了肌肉交感神经活动 (MSNA).
- 运动可能是一个有价值的策略,通过调节MSNA来改善心血管健康.
- 患有心血管疾病的个人可能特别受益于炼干预措施,以减少MSNA为目标.
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