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Updated: Jun 26, 2025

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DCM-球体形态表达PADs和cytrullinated细胞骨蛋白质

Alia Sadiq1, Justyna Fert-Bober1,2

  • 1Advanced Clinical Biosystems Research Institute, Smidt Heart Institute.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
|May 16, 2024
PubMed
概括

扩展性心肌病肌纤维细胞形成独特的球体,其中含有丁氨酸减小酶 (PAD) 酶,细胞外矩阵蛋白和素. 这些DCM球体为研究疾病特征和潜在疗法提供了一个新的体外模型.

关键词:
DCM-球形形态的变化在PAD酶的作用下,PAD酶含有鲁林的ECM.细胞骨蛋白质的细胞骨蛋白质.扩张性心肌病 (DCM) 是一种

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