神经认知在儿科叶瘤与相关的
Elise M Turner1, Emily Olsen2, Susanne Duvall2
1Section of Neurology, Department of Pediatrics, Children's Hospital Colorado/University of Colorado School of Medicine, Portland, Oregon, USA.
Developmental neuropsychology
|May 16, 2024
概括
在儿童中,与瘤相关的是常见的,可能导致神经认知障碍 (NCI). 虽然NCI比率相似,但出现了特定的认知差异,这表明可能需要不同的预后模型.
科学领域:
- 神经学 神经学
- 神经心理学 神经心理学
- 儿科瘤学 儿科瘤学
背景情况:
- 与瘤相关的是儿科叶瘤 (TLT) 患者经常出现的神经病理并发症.
- 它对神经认知障碍 (NCI) 构成重大风险.
- 这一领域仍未得到充分研究,特别是在与瘤相关的和非新发性之间区分结果时.
研究的目的:
- 为了比较患有叶瘤和 (TLT+) 的儿科患者的神经认知障碍 (NCI) 率与患有非新发性叶的儿科患者.
- 在这些独特的儿科患者群体中确定与NCI相关的因素.
- 探索对认知结果的单独预后模型的需求.
主要方法:
- 对41名年轻人 (6至20岁) 进行了神经心理评估.
- 参与者包括23名TLT+患者和18名非新发性叶患者.
- 统计分析比较了不同组的NCI率和相关因素.
主要成果:
- 在TLT+和非新发性群体中,NCI总体率在TLT+和非新发性群体之间是可比的.
- 非新发性的参与者在语音流任务上显示出更高的NCI (p=.047).
- 在TLT+参与者中,较年轻的发作发作年龄和更多的抗发作药物与NCI相关.
结论:
- 患有TLT+和非新发性的儿童群体表现出不同的认知特征.
- 对于这些群体,可能需要针对认知结果的单独预后模型.
- 需要进一步的研究来完善儿童中NCI的理解和管理.
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