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癌症诊断中的分子方法:简要的回顾

Tanushree Budhbaware¹, Jaishriram Rathored¹, Sandesh Shende¹

¹Department of 'School of Allied Health Sciences', Central Research Laboratory (CRL) and Molecular Diagnostics, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, India.

Annals of medicine

|May 16, 2024

概括

分子方法彻底改变了癌症遗传学,为识别遗传变化提供了强大的工具,并使精确医学成为可能. 本综述强调了它们对理解癌症和通过向疗法改善患者治疗结果的影响.

科学领域:

瘤学和遗传学
分子生物学分子生物学
精准医学是一门精准的医学.

背景情况:

在全球范围内,癌症仍然是导致死亡的主要原因.
分子方法在癌症研究和治疗中越来越重要.
需要对癌症中的分子方法进行全面的概述.

研究的目的:

系统地审查和总结有关癌症相关疾病分子方法的证据.
为了指导临床实践和癌症遗传学的未来研究.
评估分子诊断和治疗方法的有效性和安全性.

主要方法:

在数据库 (PubMed,Google Scholar,WoS,Scopus) 中进行全面的文献搜索.
包括关于癌症遗传学,遗传性癌症,风险评估,诊断工具,查,生物标志物和分子诊断的研究.
不包括不涉及遗传或分子诊断的研究.

主要成果:

分子方法通过识别关键的遗传变化,改变了癌症遗传学.
这些见解确切地确定了瘤原因驱动因素和治疗点.
这促进了精准医学方法,以改善患者的治疗结果.

结论:

分子方法正在彻底改变瘤学,为了解癌症在遗传层面的复杂性提供了工具.
这些技术提高了对癌症病因,进展和治疗反应的理解.
它们为个性化医疗和向治疗开辟了新的途径,改善了患者的治疗结果.

关键词:

分子技术分子技术.癌症的诊断癌症的诊断癌症遗传学癌症遗传学下一代测序的下一代测序.聚合酶连锁反应的发生.

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