语言和空间工作记忆对运动皮层中短时间和长时间延迟的感觉运动电路的影响
Markus W Lenizky1, Sean K Meehan1
1Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
PloS one
|May 16, 2024
概括
来自口头工作记忆的认知负载特别影响感觉运动回路,影响后部-前部 (PA) 短延迟附着抑制 (SAI),但不影响前部-后部 (AP) 路径或长延迟抑制 (LAI). 空间负载没有影响.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 认知神经科学 认知神经科学
背景情况:
- 感官运动控制依赖于可适应的运动皮质电路.
- 影响性抑制非侵入性地探测认知和程序控制之间的相互作用.
- 跨磁刺激 (TMS) 特性揭示了传感运动电路对抑制的贡献.
研究的目的:
- 研究语言和空间工作记忆负载如何影响感觉运动电路.
- 为了区分TMS诱导的后前 (PA) 和前后 (AP) 电流对 afferent 抑制的影响.
- 检查工作记忆负载对短延迟关联抑制 (SAI) 和长延迟关联抑制 (LAI) 的影响.
主要方法:
- 在口头 (字母组) 和空间 (位置组) 工作记忆任务中评估SAI和LAI.
- 操纵的TMS电流方向 (PA与AP) 在 afferent抑制测量期间.
- 在低 (2项) 和高 (6项) 工作内存负载下比较抑制水平.
主要成果:
- 后部-前部 (PA) SAI随着语言工作记忆负载的增加而下降.
- 前后 (AP) SAI和所有长延迟附带抑制 (LAI) 测量都不受语言或空间工作记忆负载的影响.
- 视觉空间工作记忆负载没有调节PA或APSAI或LAI.
结论:
- 研究结果支持多个融合的传感运动循环具有不同的功能角色.
- 特定的感觉运动电路 (PA,短延迟) 对口头工作记忆需求敏感.
- 这种分离突出了特定于环境的脊柱上控制机制.
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