久坐不动行为和教育水平在乳腺癌风险中的相互作用
Marina Pinto-Carbó1, Mercedes Vanaclocha-Espí1, Josefa Ibañez1,2
1Cancer and Public Health Research Unit, Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO-Public Health), Valencia, Spain.
PloS one
|May 16, 2024
概括
久坐不动的行为,特别是每天坐2个小时以上,会增加教育程度较低的女性患乳腺癌的风险. 绝经后妇女和那些有孩子的妇女,这种风险更高.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 健康的社会决定因素
背景情况:
- 久坐不动行为是一个日益严重的公共卫生问题.
- 了解其与乳腺癌 (BC) 风险的联系对于预防策略至关重要.
- 社会经济因素可能会改变这种关系.
研究的目的:
- 分析静坐行为与乳腺癌风险之间的关联.
- 研究社会经济因素,特别是教育水平在这种关系中的作用.
主要方法:
- 瓦伦西亚地区乳腺癌查计划 (2018-2019) 中的121,359名45-70岁妇女的横截面研究 (2018-2019).
- 静坐行为分类为每天数小时 (≤2,>2-≤3,>3-≤5,>5).
- 嵌套后勤回归模型根据年龄,家族史,荷尔蒙/生殖因素,生活方式,社会经济地位和性别变量进行调整.
主要成果:
- 总体而言,久坐 (>2小时/天) 的行为显示出非显著的趋势,导致BC风险增加.
- 低教育水平的女性在久坐 (>每天2小时) 时,BC风险显著增加.
- 这种增加的风险在绝经后妇女和低教育群体中活产妇女中尤为明显.
结论:
- 每天坐2个小时以上与更高的乳腺癌风险有关.
- 这种关联对于教育程度低的女性来说很重要.
- 绝经后的状态和活产子进一步提高了社会经济水平较低的群体的风险.
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