在PTSD严重程度和疼痛结果的性别差异:从LAMP试验的基线结果
Jessica K Friedman1, Brent C Taylor2,3, Emily Hagel Campbell2
1VA HSR&D Center for the Study of Healthcare Innovation, Implementation and Policy, VA Greater Los Angeles Health Care System (VAGLACS), Los Angeles, California, United States of America.
PloS one
|May 16, 2024
概括
创伤后应激障碍 (PTSD) 和慢性疼痛在退伍军人中具有很强的联系,PTSD症状加剧了疼痛结果. 这项研究发现,PTSD严重程度如何影响老兵患有慢性疼痛的疼痛没有显著的性别差异.
科学领域:
- 精神病学是一个精神病学.
- 疼痛医学 医学 疼痛医学
- 退伍军人健康 退伍军人的健康
背景情况:
- 创伤后应激障碍 (PTSD) 和慢性疼痛经常同时发生,特别是在退伍军人中.
- 双重诊断导致更严重的健康结果.
- 有限的研究已经探索了与PTSD严重程度相关的疼痛结果的性别特异性差异.
研究的目的:
- 调查创伤后应激障碍症状和疼痛结果之间的关系中的性别差异.
- 关注参与慢性疼痛临床试验的退伍军人.
主要方法:
- 使用了等级线性回归模型.
- 分析了421名男性和386名女性退伍军人慢性疼痛的数据.
- 检查了PTSD症状严重程度和疼痛灾难化,强度和干扰之间的关联.
主要成果:
- 创伤后应激障碍症状与增加的疼痛灾难化,强度和干扰有显著的相关性.
- 在这些协会中没有观察到统计学上显著的性别差异.
- 这在原始模型和调整后的模型中都是如此.
结论:
- 这些发现表明,慢性疼痛和PTSD之间存在潜在的相互维持周期.
- 疼痛感觉可能会引发PTSD症状,特别是当与相同的创伤事件相关时.
- 强调需要综合治疗方法,同时出现慢性疼痛和PTSD.
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