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Updated: Jun 26, 2025

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
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来自细胞因子激活的CD8+ T细胞的细胞外囊泡的抗瘤作用

Lin Zhang1,2,3,4,5, Yuan Meng1,2,3,4,5, Yang An1,2,3,4,5

  • 1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Huanhuxi Road, Tiyuanbei, Hexi District, Tianjin 300060, China.

Journal of leukocyte biology
|May 16, 2024
PubMed
概括

由细胞因子激活的CD8+T细胞衍生的细胞外囊泡 (caCD8-EVs) 显示出直接的抗瘤活性. 这些EV含有细胞毒蛋白和干扰素-,诱导癌细胞亡.

关键词:
IFNγ IFNγ 的意思是细胞因子激活的CD8+ T细胞细胞因子诱导的杀手细胞.细胞毒性 细胞毒性细胞外囊泡中的细胞外囊泡.

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