环境和婴儿的成长:婴儿养和早期发育研究
Danielle R Stevens1, Mandy Goldberg1, Margaret Adgent2
1Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC 27709, USA.
The Journal of clinical endocrinology and metabolism
|May 16, 2024
概括
婴儿早期接触常见的内分泌干扰物与更高的体重指数 (BMI) 和更快的BMI增加有关. 这表明潜在的长期健康风险,包括肥胖和心脏代谢问题.
科学领域:
- 环境健康 环境健康
- 儿科内分泌学 儿科内分泌学
- 毒理学 毒理学 毒理学
背景情况:
- 婴儿体重指数 (BMI) 快速增加与晚期肥胖有关.
- 暴露于诸如类的内分泌干扰化学物质可能会影响婴儿的BMI.
- 类是常见的环境污染物,具有潜在的健康影响.
研究的目的:
- 调查美国前队列中环境暴露和婴儿BMI之间的关联.
- 为了检查早期的醇暴露如何影响婴儿的BMIz-score水平和轨迹.
主要方法:
- 在199名6-8周和12周的婴儿中测量了尿.
- 评估BMIz-score通过12次访问到36周的年龄.
- 使用平均差异和相对风险比率分析了平均早期和BMIz-score之间的关联.
主要成果:
- 索-3,甲基,和联合与更高的平均BMIz-score相关.
- 基-3,二基和联合与快速BMIz-score轨迹的风险增加有关.
- 特定的醇与BMI水平和生长模式都有显著的关联.
结论:
- 早期婴儿暴露于醇与平均BMIz-score增加和BMI快速增加有关.
- 这些发现表明早期暴露于的潜在的长期心脏代谢后果.
- 环境中的暴露是婴儿生长和预防肥胖的关键因素.
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