烟草戒烟与病工人气流阻塞的关联:一个队列研究
Shuyuan Yang1, Chi Kuen Chan2, Maggie Haitian Wang1
1Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
PloS one
|May 16, 2024
概括
戒烟显著降低了工人的空气流阻塞 (AFO) 风险. 3年后便会出现好处,这强调了戒烟对于暴露于的个体的肺部健康的重要性.
科学领域:
- 职业医学 职业医学是专业的.
- 肺部医学 肺部医学
- 流行病学 流行病学
背景情况:
- 在一般人群中,烟草吸烟与空气流阻塞 (AFO) 有关.
- 吸烟和AFO之间的关联在暴露于粉的工人中研究较少.
- 病是一种肺部疾病,是由吸入粉引起的.
研究的目的:
- 调查吸烟和AFO在暴露于二氧化粉的工人之间的关联.
- 评估戒烟对该群体的AFO发展的影响.
主要方法:
- 对4481名工人 (1981-2019) 的回顾性队列研究.
- 对终身工作历史和吸烟习惯的分析.
- 在诊断时和平均9.4年的随访后进行螺旋计.
- AFO定义为FEV1/FVC <正常的下限 (LLN).
- 用于评估关联和停止效应的多变量逻辑和考克斯回归.
主要成果:
- 当前吸烟者 (OR=1.92) 和前吸烟者 (OR=2.09) 的AFO的几率明显更高.
- 在戒断后的前三年,AFO风险增加 (OR=1.23) 但随着戒断时间的延长而下降.
- 戒烟降低了AFO风险,无论是在 (HR=0.58) 和 (HR=0.62) 诊断出病之前.
结论:
- 戒烟显著降低了有病的工人的AFO风险.
- 戒烟的健康益处在禁食3年后变得明显.
- 早期和持续的戒烟对于暴露于的工人来说至关重要.
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