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Updated: Jun 26, 2025

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阿尔法Fold2结构指导潜在的连接体发现

Jiankun Lyu1,2, Nicholas Kapolka3, Ryan Gumpper3

  • 1Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|May 16, 2024
PubMed
概括

AlphaFold2模型通过准确预测配体结合部位,显示出药物发现的前景. 这项研究表明它们在潜在的对抗关键受体的新药候选者的有效性.

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