1型麻醉症儿童和青少年患者的执行功能表现
Mengmeng Wang1, Chaoran Shen2, Xinran Liu1
1School of Nursing, Peking University, Beijing, China; Division of Sleep Medicine, Peking University People's Hospital, Beijing, China.
Sleep medicine
|May 16, 2024
概括
患有1型麻醉症 (NT1) 的儿童和青少年表现出执行功能受损,与睡眠问题有关. 早期的神经心理评估和干预对这些患者至关重要.
科学领域:
- 神经科学是一个神经科学.
- 儿科神经学 儿科神经学
- 睡眠医学 睡眠医学
背景情况:
- 有限的研究存在于小儿麻醉症1型 (NT1) 患者的执行功能.
- 了解这一群体的执行功能缺陷对于有效管理至关重要.
研究的目的:
- 评估中国儿童和青少年NT1.1的执行功能.
- 确定影响这些患者执行功能的因素.
- 评估短期治疗对执行功能的影响.
主要方法:
- 53名NT1患者和37名健康对照对执行功能领域进行了神经心理测试.
- 自我报告的措施评估了嗜睡,抑郁,焦虑和睡眠质量.
- 在正常药物治疗三天后,NT1患者被重新评估.
主要成果:
- 与对照组相比,NT1患者表现出较差的执行功能 (处理速度,抑制控制,认知灵活性).
- 执行功能缺陷与睡眠参数相关,如睡眠效率和延迟.
- 短期治疗改善了NT1患者的抑制控制,认知灵活性和工作记忆.
结论:
- 儿科NT1患者的执行功能受损,并与睡眠参数相关.
- 神经心理评估和早期干预对于患有NT1的儿童和青少年至关重要.
相关概念视频
Narcolepsy
101
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
101
Sleep-Wake Cycles
1.3K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.3K
Attention-Deficit/Hyperactivity Disorder
56
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
56
Information Processing Approach
33
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
33
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
120
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
120
Management of Insomnia
244
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
244


