在婴儿和幼儿中缺乏营养素的评估主要是以氨基酸为基础的元素配方:一项探索性研究
Ichiro Takeuchi1, Rie Funayama1, Hiromichi Shoji2
1Division of Gastroenterology, Center for Pediatric Inflammatory Bowel Disease, National Center for Child Health and Development, Tokyo, Japan.
Annals of nutrition & metabolism
|May 16, 2024
概括
用于IBD和EGID的婴儿和幼儿的基本配方 (EF) 可能导致必需脂肪酸,和酸的缺乏. 长期使用也可能导致氨基酸失衡.
科学领域:
- 儿童营养学 儿童营养学
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
背景情况:
- 患有炎症性肠病 (IBD) 和eosinophilic胃肠疾病 (EGID) 的婴儿和幼儿通常依赖元素配方 (EFs) 作为其主要营养.
- 评估这种脆弱人群的营养缺乏,对于确保足够的生长和发展至关重要.
研究的目的:
- 评估患有IBD和EGID的6个月至6岁儿童的营养状况,这些儿童主要食用EFs.
- 为了确定与长期基本配方养相关的特定营养缺乏和不平衡.
主要方法:
- 一项比较研究涉及21名儿童食EF (EF组) 和25名健康对照 (CL组).
- 分析了包括,脂溶性维生素,酸,脂肪酸 (通过三烯:四烯比率) 和氨基酸在内的营养水平.
- 进行了统计分析,以比较两组之间的营养水平.
主要成果:
- 与对照组相比,EF组表现出明显较低的和酸水平.
- 虽然在一些EF参与者中发现了脂肪溶性维生素缺乏,但没有发现任何显著的群体差异.
- EF组显示出较高的三烯:四烯比率,表明必需脂肪酸缺乏,并经历了氨基酸不平衡 (较低的阿斯巴拉金和牛,较高的氨酸和氨酸).
结论:
- 在患有IBD和EGID的婴儿和幼儿中,长期使用基本配方食与必需脂肪酸,和酸的缺乏有关.
- 在这个儿科群体中,元素配方也可能存在氨基酸失衡的风险.
- 建议对长期EFs的儿童进行特定营养缺乏症的临床监测.
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