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Updated: Jun 26, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

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针对17β-基类固醇脱酶7型抑制剂的合成和表征

Jean-Yves Sancéau1, René Maltais1, Ming Zhou2

  • 1Organic Synthesis Service, CHU de Québec Research Center-Université Laval, Québec, QC G1V 4G2, Canada; Endocrinology and Nephrology Unit, CHU de Québec Research Center-Université Laval, Québec, QC G1V 4G2, Canada.

The Journal of steroid biochemistry and molecular biology
|May 16, 2024
PubMed
概括

新的碳酸衍生物被合成并评估为17β-基固醇脱酶7型 (17β-HSD7) 的抑制剂. 化合物4具有C17-spiranicE环,表现出对17β-HSD7的优越抑制活性,为荷尔蒙依赖癌症治疗提供了一个有前途的途径.

关键词:
17β-Hydroxysteroid脱酶类型 7 的 7β-Hydroxysteroid脱酶类型 7 的 17β-Hydroxysteroid脱酶类型 7 的 17β-Hydroxysteroid脱酶类型 7 的 17β-Hydroxysteroid脱酶类型乳腺癌 乳腺癌 乳腺癌化学合成 化学合成酶抑制剂是一种酶抑制剂.这是一种类固醇.

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