在基于例行收集的健康数据的研究中验证算法:一般原则
Vera Ehrenstein1, Maja Hellfritzsch2,3, Johnny Kahlert1
1Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, 8200 Aarhus N, Denmark.
American journal of epidemiology
|May 16, 2024
概括
与真实世界数据 (RWD) 使用的算法验证对于可靠的医疗保健证据至关重要. 本文为使用RWD进行算法验证研究的方法和最佳实践提供了指导.
科学领域:
- 现实世界数据 (RWD) 分析分析.
- 药学流行病学 药学流行病学
- 医疗信息学 医疗信息学
背景情况:
- 决策者越来越多地使用来自健康和行政数据库的真实世界数据 (RWD).
- 算法对于定义RWD研究中的变量至关重要,识别特定的健康状况或特征.
- 确保算法有效性对于生成可靠的证据来支持基于证据的医疗保健至关重要.
研究的目的:
- 为验证基于RWD的算法系统化术语,方法和实际考虑.
- 为进行强大的算法验证研究提供框架.
- 提高从RWD获得的证据的可信度.
主要方法:
- 讨论算法准确度指标和黄金/参考标准.
- 考虑研究规模,优先考虑准确度指标和算法可移植性.
- 强调验证决策和结果解释的透明度.
主要成果:
- 算法的有效性必须在特定数据源的背景下进行评估.
- 确定有效性指标的优先级取决于变量在分析中的作用 (例如,资格,暴露,结果).
- 验证应该是常规RWD源维护的一个组成部分.
结论:
- 对RWD算法的系统验证是有效研究结果的先决条件.
- 对特定环境的评估和对算法有效性的透明报告是必不可少的.
- 持续的验证工作确保了RWD在医疗保健决策中的持续实用性和可靠性.
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