在口腔中COVID-19疫苗接种后的效果:系统性审查
Anubhuti Sood1, Sreevatsan Raghavan1, Deepika Mishra2
1Translational Health Science and Technology Institute, Faridabad, India.
Evidence-based dentistry
|May 16, 2024
概括
接种COVID-19疫苗可能会导致免疫介导的口服不良事件,特别是在女性和老年患有并发症的人群中. mRNA疫苗可能显示出更高的倾向于这些口腔病变.
科学领域:
- 免疫学 免疫学 免疫学
- 口腔医学是指口腔医学.
- 疫苗学 疫苗学 疫苗学
背景情况:
- 由于SARS-CoV-2的全球传播,需要进行广泛的疫苗接种.
- 报道了COVID-19疫苗接种后的不良事件.
- 与疫苗相关的不良事件的口服表现需要调查.
研究的目的:
- 系统地审查和调查COVID-19疫苗接种后的口服不良事件.
主要方法:
- 对五个数据库进行了系统的搜索.
- 包括病例报告,病例系列和有关疫苗接种后口腔病变的观察性研究.
- 质量评估使用了乔安娜·布里格斯研究所的批判性评估工具.
主要成果:
- 在接种疫苗后发现了18个单独的口腔病变病例.
- 大多数病变发生在BNT162b2疫苗接种后,平均发病年龄为59.94岁.
- 女性 (67%) 主要受到影响,高血压是最常见的并发症.
结论:
- 接种COVID-19疫苗可以引发免疫介导的口腔事件.
- 基于mRNA的疫苗可能与口服不良反应的相关性更高.
- 女性,老年人和患有并发症的人可能面临疫苗接种后口腔病变的风险增加.
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