宫内受精时间模型-LH只能带你到目前为止
Michal Youngster1,2, Eden Moran3, Almog Luz3
1IVF Unit, Department of Obstetrics and Gynecology, Shamir Medical Center, Assaf Harofeh, 70300, Zerifin, Israel. michalyo@gmail.com.
Journal of assisted reproduction and genetics
|May 16, 2024
概括
一个LH值算法在75%的自然周期中准确预测了子宫内授精 (IUI) 的时间. 一个3激素的人工智能模型显示了优越的预测准确度,以优化IUI时间.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 人工智能在医学中的应用
背景情况:
- 准确预测排卵时间对于自然循环子宫内授精 (NC-IUI) 的成功至关重要.
- 目前的方法通常依赖于黄素化激素 (LH) 值,但它们的预测准确性可能是可变的.
研究的目的:
- 评估最佳LH值算法的准确性,以预测NC-IUI的排卵时间.
- 将LH值算法的性能与多激素AI模型进行比较,以预测IUI时间.
主要方法:
- 对2467个自然周期 (2018-2022) 的回顾性队列研究.
- 由先前开发的AI模型决定的排卵时间.
- 应用了一个低 (11 mIU/ml) 和高 (40 mIU/ml) 值的LH值算法.
主要成果:
- 在75.4%的病例中,LH值算法正确预测了IUI时间.
- 该算法在23.1%的病例中产生了"错误"预测,表明潜在的非最佳授精时间.
- 一个3激素 (LH,雌激素,孕激素) 的AI模型实现了显著更高的成功率 (93.6%) 与较低的错误率 (4.3%).
结论:
- 虽然反映了常规做法,但LH值算法在安排IUI时间方面表现出适度的准确性.
- 在AI模型中整合多种激素 (LH,雌激素,孕激素) 为准确预测最佳IUI时间提供了显著的优势.
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