从土耳其的家禽中罕见地分离的沙门氏菌血清型的抗生素耐药性概况
Hamit Kaan Müştak1, Seyyide Sarıçam İnce1, İnci Başak Müştak2
1Ankara University, Faculty of Veterinary Medicine, Department of Microbiology, Ankara, Turkey.
Veterinaria italiana
|May 17, 2024
概括
这项研究监测了沙门氏菌的抗生素耐药性,发现S. Agona和S. Heidelberg是最耐药的. 对沙门氏菌和抗生素耐药性基因的持续监测对公共卫生至关重要.
科学领域:
- 兽医微生物学 兽医微生物学
- 食品安全 食品安全
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 沙门氏菌物种是全球抗生素耐药性基因 (ARG) 传播的重要贡献者.
- 了解各种沙门氏菌血清型的耐药性概况对于公共卫生和食品安全至关重要.
- 该研究的重点是2014-2017年间分离的沙门氏菌血清型.
研究的目的:
- 研究多种沙门氏菌血清型的表型抗生素耐药性概况.
- 在这些血清型中检测特定抗生素耐药性基因 (ARG) 的存在.
- 评估单独的沙门氏菌菌株中多药耐药性 (MDR) 的流行情况.
主要方法:
- 通过对12种抗微生物药物的磁盘扩散试验来确定表型抗生素耐药性.
- 用聚合酶链反应 (PCR) 来检测ARG的存在.
- 对抗生素敏感性测试对八种研究的沙门氏菌血清型中的五种菌株进行了测试.
主要成果:
- 沙门氏菌Agona和沙门氏菌海德堡表现出最高水平的耐药性.
- 沙门氏菌科卡是最敏感的血清型.
- 多种药物耐药性 (MDR) 在S. Agona中最常见,其次是S. Saintpaul,S. Hindmarsh和S. Ottmarchen.
- 在抗四环素菌株中,tet (A) 基因是最常见的.
- 敏感性对氨基醇和塞夫塔齐迪姆是最高的;耐药性对硫胺是最高的.
结论:
- 持续监测沙门氏菌种类. 它们的ARG对于保护人类,动物和环境健康至关重要.
- 这项研究强调了需要明智地使用抗生素的必要性,即使对于很少被孤立的沙门氏菌血清型.
- 沙门氏菌传播的ARG可以导致MDR细菌的出现,构成严重的公共卫生威胁.
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