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在一个2岁的小孩的原性结肠炎的二次蛋白质损失肠病
Hamza Hassan Khan1, David N Lewin2, Carmine Suppa1
1Department of Pediatrics, Division of Pediatric Gastroenterology, Shawn Jenkins Children's Hospital Medical University of South Carolina Charleston South Carolina USA.
JPGN reports
|May 17, 2024
概括
在患有质结肠炎 (CC) 的儿童中,蛋白质损失肠病 (PLE) 是罕见的. 本案例研究详细介绍了一名患有CC相关PLE的2岁女孩,她成功地对布松胺治疗做出了反应.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 胃肠道病理 胃肠道病理
- 罕见疾病 罕见疾病
背景情况:
- 与质结肠炎 (CC) 相关的蛋白质丧失肠道病变 (PLE) 在儿科患者中很少被记录.
- 这种情况可以表现为显著的低albuminemia和营养物质吸收不良.
研究的目的:
- 描述了一种罕见的儿科原性结肠炎病例,呈现出蛋白质损失肠道病变.
- 要突出在这种情况下的诊断和治疗方法.
主要方法:
- 一个2岁的女性病例报告,出现了发烧,水性腹和减少口服摄入的症状.
- 实验室评估显示,严重的低albuminemia,泛cytopenia,以及便α-1-antitrypsin的升高.
- 内镜评价与正常的粘膜外观,但组织学证实原性结肠炎.
主要成果:
- 患者出现了严重的低albuminemia (1.5 g/dL) 和全细胞减小.
- 组织学检查证实了结肠杆菌性结肠炎,尽管内镜检查结果正常.
- 布索尼德治疗了12周,导致症状完全消失,实验室值正常化.
结论:
- 在幼儿中,质结肠炎可以呈现为蛋白质损失性肠病.
- 布德索尼德是一种有效的治疗选择,用于患有蛋白质损失肠病的儿科原性结肠炎.
- 通过适当的管理,可以实现长期缓解.
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