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嗅觉神经母细胞瘤的临床结果

Akira Nakazono¹, Hiroaki Motegi², Masanobu Suzuki¹

¹Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Frontiers in oncology

|May 17, 2024

概括

这项研究评估了嗅觉神经母细胞瘤 (ONB) 的治疗方案. 与开放式手术相比,内镜骨底部手术 (ESBS) 显示出较低的并发症率和更好的术后数据的良好结果.

科学领域:

在瘤学瘤学.
神经外科神经外科
耳鼻喉科耳鼻喉科耳鼻喉科

背景情况:

嗅觉神经母细胞瘤 (ONB) 是一种罕见的恶性瘤.
对ONB的标准治疗方案各不相同.
本研究评估了针对ONB的特定机构治疗方案.

研究的目的:

评估嗅觉神经母细胞瘤 (ONB) 特定治疗方案的结果.
为了比较内镜骨底部手术 (ESBS) 与骨切除术 (ESBS) 结合ONB的疗效和周围手术数据.

主要方法:

对ONB患者的回顾性审查.
对生存结果和术后数据的分析.
用ESBS治疗的患者,用ESBS进行头骨切割或化学辐射疗法 (CRT).

主要成果:

有利的生存率:5年总生存率为92.9%,10年总生存率为82.5%.
内镜骨底部手术 (ESBS) 组显示显著缩短操作时间,出行,住院和少失血.
在ESBS组中,并发症率较低,外科手术后期结果更好.

结论:

对ONB的评估治疗方案产生了有利的结果.
内镜骨底部手术 (ESBS) 是选择ONB病例的安全有效方法.
与开放方法相比,ESBS在减少并发症和改善外科手术期间的数据方面具有优势.

关键词:

进行了骨切除术 (craniotomy).内镜头骨底部手术术镜头骨基手术这是一个神经母细胞瘤.诱导化疗是一种诱导化疗.嗅觉神经母细胞瘤在术后进行放射治疗.

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