对人类全身癌症口腔微生物群的洞察力
Lan Su1, Rui Yang1, Yanan Sheng1
1Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, China.
Frontiers in microbiology
|May 17, 2024
概括
像细菌和真菌这样的口腔微生物可以引起癌症. 本综述探讨了口腔微生物群如何促进癌症,以及它们在癌症预防和治疗中的潜力.
科学领域:
- 微生物学 微生物学
- 在瘤学瘤学.
- 口腔健康 口腔健康
背景情况:
- 口腔是身体与环境之间的关键接口.
- 口腔微生物越来越多地与全身癌症,特别是口腔癌有关.
- 特定的细菌,如 Porphyromonas gingivalis 和 Fusobacterium nucleatum,以及口腔真菌和病毒,都与各种癌症有关.
研究的目的:
- 综合审查口腔微生物群对致癌产生有助的致病机制.
- 探索口腔微生物群在癌症预防,查和治疗中的潜在应用.
- 为研究口腔微生物群与全身癌症之间的联系的研究人员提供资源.
主要方法:
- 对口腔微生物群和癌症现有研究的文献综述.
- 对研究致癌的微生物机制的研究进行分析.
- 综合有关口腔微生物群在癌症发展中的作用和潜在治疗策略的信息.
主要成果:
- 口腔微生物群可以通过炎症,免疫抑制和改变瘤微环境等机制促进致癌.
- 微生物平衡和口腔微生物群迁移的扰乱对于瘤功能至关重要.
- 特定的口腔细菌,真菌和病毒与不同类型的癌症有关.
结论:
- 口腔微生物群在全身癌症的发展中发挥着重要作用.
- 了解这些机制为新的癌症预防,查和治疗策略提供了潜力.
- 需要进一步的研究,以充分阐明口腔微生物群与癌症之间的复杂关系.
关键词:
杆菌核酸 (Fusobacterium nucleatum) 是一种细菌.葡萄牙牙牙病 Porphyromonas gingivalis 这种虫害的癌症发生的原因是癌症发生.口腔中的微生物群.系统性癌症 系统性癌症更多相关视频
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