围绕灾难的伪装者:在日本福岛的草伤寒的临床特征
Masashi Narita1,2,3, Naota Monma4, Kazuki Chiba5
1Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Nambu Medical Center & Children's Medical Center, Haebaru, Japan.
Open forum infectious diseases
|May 17, 2024
概括
福岛的草伤寒往往呈现异常,延迟了诊断和治疗. 本综述强调了由于非标准症状导致的灌木伤寒 (ST) 病例识别的挑战.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 临床医学 临床医学
背景情况:
- 灌木伤寒 (ST) 是日本福岛的流行病,报告的病例数量很大.
- 由于ST的多样化和非典型的临床表现,延迟诊断ST是常见的.
- 早期和准确的诊断对于有效治疗性传播疾病至关重要.
研究的目的:
- 审查福岛成年患者草伤寒的临床特征.
- 根据临床表现,确定诊断草原伤寒的挑战.
- 分析ST的典型和非典型特征和并发症的频率.
主要方法:
- 通过血清学和PCR确认的55例灌木伤寒病例的回顾性审查.
- 2008年至2017年间,从奥塔尼希努奇总医院的成年患者中收集的数据.
- 分析临床特征,诊断延迟,治疗结果和并发症.
主要成果:
- 大多数病例 (69%的平均年龄) 是女性,死亡率为1.8%.
- 大约70%的患者最初没有被诊断为ST,22%的患者接受了不适当的抗生素.
- 非典型的表现很常见,其中31%缺乏典型的症状 (发烧,皮疹,疹) 和11%没有疹.
结论:
- 当典型的临床特征缺失时,诊断草原伤寒是具有挑战性的.
- 非典型的表现和多系统参与在福岛特有ST种群中很常见.
- 对各种临床表现的认识对于及时的ST诊断和管理至关重要.
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