评估后急性COVID-19和长期COVID症状,使用问卷:在一年内进行纵向研究
Canan Emiroglu1, Murat Dicle1, Serap Demirelli Ozagar1
1Department of Family Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkiye.
Northern clinics of Istanbul
|May 17, 2024
概括
许多COVID-19幸存者经历了持续的症状,称为后急性COVID-19综合征 (PCS). 在非住院患者中,虚弱和关节痛更为常见,女性与持久症状的关联性更强.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 神经学 神经学
背景情况:
- 长期影响的COVID-19,或后急性COVID-19综合征 (PCS),呈现一个重要的全球卫生挑战.
- 在最初感染后,PCS的特点是广泛的持续症状.
研究的目的:
- 定义PCS患者的症状的存在和谱.
- 评估持续症状的频率和相关因素.
主要方法:
- 一项纵向研究采访了487名被诊断患有严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 的成年人.
- 采集的数据包括人口统计,并发症和症状,通过在三个面对面访问期间进行的160个问题调查.
- 统计分析涉及单变量比较和多重物流回归.
主要成果:
- 最常见的PCS最初症状是呼吸不全,虚弱,遗忘,疲劳和关节痛.
- 这些症状在出院后的6个月或更长时间内在患者中持续存在,在第三次访问时发生率下降,但前五种症状保持一致.
- 在非住院患者中,虚弱和关节痛更为频繁,女性表现出与持久性关节痛的最强相关性.
结论:
- 很大一部分COVID-19幸存者经历了持续的症状,感染后长达一年.
- 并发症和吸烟状态与PCS症状严重程度没有相关性.
- 了解PCS机制和诱导因素需要一个多学科的方法.
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