心肺运动测试,计算机断层扫描衍生的身体组成,系统性炎症和选择性腹腔大动脉动脉瘤修复后的生存率:一个回顾性队列研究
Nicholas A Bradley1, Josh McGovern, Christina Beecroft
1From the University of Glasgow, Glasgow (NAB, JM, CSDR, DCM, GJKG) and NHS Tayside, Dundee, UK (CB).
European journal of anaesthesiology
|May 17, 2024
概括
心肺运动测试 (CPEX) 没有预测腹腔大动脉动脉瘤 (AAA) 患者的存活率. 然而,CT衍生的肉症得分 (CT-SS) 独立预测了这些患者的长期死亡风险.
科学领域:
- 血管外科 血管外科
- 老年医学 老年医学
- 放射学 放射学是指放射学
背景情况:
- 在腹腔大动脉动脉瘤 (AAA) 干预之前,选择性地使用心肺运动测试 (CPEX).
- 通过CT-derived body composition (CT-BC) 评估的萨尔科佩尼亚与全身炎症和骨肌功能降低有关.
- 了解生存预测因素对于AAA患者管理至关重要.
研究的目的:
- 调查CT-BC,CPEX,炎症和接受选择性AAA修复的患者的生存率之间的关联.
- 在AAA患者中确定肉类和CPEX的预后值.
主要方法:
- 来自单一中心的176名患者 (EVAR/OSR) 的回顾性分析 (2015-2020).
- 收集了手术前的CPEX数据和CT扫描来评估肉症 (CT-SS).
- 系统性炎症使用修改后的格拉斯哥预后评分 (mGPS) 进行评估.
主要成果:
- 较高的CT肉症得分 (CT-SS) 与显著降低的平均存活率 (P=.01) 相关.
- 升高的CT-SS独立预测了长期死亡风险的增加 (HR1.83,P<.01).
- CPEX结果显示,与CT-BC或生存的独立预后值 (P>.05) 没有显著的关联.
结论:
- CT-SS (CT-derived sarcopenia assessment) 是可选AAA修复患者长期生存的有价值的预后工具.
- 在这个患者队列中,CPEX测试没有显示出一致的预后效用.
- 与CPEX相比,身体组成分析可能为AAA干预规划提供更好的风险分层.
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