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洞察G蛋白结合受体螺旋8溶液的结构和方向,使用神经酶受体1

James B Bower1, Scott A Robson2, Joshua J Ziarek1,2

  • 1Molecular and Cellular Biochemistry Department, Indiana University, Bloomington, Indiana, USA.

Protein science : a publication of the Protein Society
|May 17, 2024
PubMed
概括

这项研究表明,神经激素受体1 (NTS1) 螺旋8和C端尾部 (H8-Ctail) 的稳定性和结构取决于膜性质. 脂微粒稳定H8,而LMNG等洗剂则没有,显示出适应性行为.

关键词:
一个A类的GPCRR.动力学 动力学 动力学螺旋波是一种螺旋波.螺旋稳定性的稳定性膜蛋白是一种膜蛋白质.核磁共振 (NMR) 是一种核磁共振技术.偏磁性放松增强剂 (PRE) 的使用

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