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Updated: Jun 26, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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致癌复合突变可以通过共同突变和它们的染色体位置来预测

Asli Küçükosmanoglu1, Carolien L van der Borden1, Lisanne E A de Boer1

  • 1Department of Neurosurgery, Brain Tumor Center Amsterdam, Amsterdam University Medical Center, Cancer Center Amsterdam, The Netherlands.

Molecular oncology
|May 17, 2024
PubMed
概括

复合突变,即在一个基因中发生多个遗传事件,可以导致治疗耐药性. 这项研究预测了这些突变,使用同时发生的突变来识别有风险的患者.

关键词:
复合突变是一种复合突变.遗传异质性的遗传异质性平行进化的平行演化.预测模型是一个预测模型.治疗耐药性 治疗耐药性

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