基于正念的干预对神经行为功能及其与早产年轻青少年大规模大脑网络的关联的影响
Vanessa Siffredi1,2,3, Maria Chiara Liverani1,4, Natalia Fernandez1
1Division of Development and Growth, Department of Paediatrics, Gynaecology and Obstetrics, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Psychiatry and clinical neurosciences
|May 17, 2024
概括
正念训练改善了早产的青少年的执行功能. 这些改善与大脑网络活动的变化有关,特别是与自我调节和注意力相关的领域.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 临床心理学 临床心理学
背景情况:
- 非常早产 (VPT) 的青少年具有更高的执行,行为和社会情绪挑战的风险.
- 基于正念的干预措施 (MBI) 在增强这些认知和情感能力方面表现有前途.
研究的目的:
- 为了检查8周的MBI如何影响VPT青少年的执行,行为和社会情绪功能.
- 为了研究MBI诱导的神经行为变化和在休息期间大规模大脑网络动态的改变之间的关联.
主要方法:
- 32名VPT青少年接受了神经行为评估和休息状态fMRI在8周的MBI之前和之后.
- 使用创新驱动的协作激活模式框架应用了动态功能连接分析.
- 可靠的变化指数量化了干预后的改善,多变量分析探索了行为和神经变化之间的联系.
主要成果:
- 在MBI前,VPT青少年表现出较低的执行和社会情绪功能,与MBI前的满期出生对照相比.
- 在MBI之后,所有以前减少的措施都出现了显著的改善.
- 增强的执行功能与前临界,杏仁体-海马体,背侧前额和视觉网络的激活持续时间的可靠变化相关.
结论:
- 在VPT青少年中,MBI有效地改善了执行功能.
- 这些功能增长与关键大脑网络的时间动态的显著,可靠的变化有关.
- 观察到的神经变化支持MBI在增强自我调节,注意力控制和感官意识方面的作用.
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