相关实验视频

Updated: Jun 9, 2026

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions
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Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions

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通过原生自上而下的质谱学研究Neomycin B不同RNA结合基因的分子内竞争

Sarah Viola Heel1, Kathrin Breuker1

  • 1Institute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.

ChemPlusChem
|May 17, 2024
PubMed
概括

了解小分子与RNA结合是药物发现的关键. 这项研究使用质谱法揭示了neomycin B如何与RNA结合,确定了可以指导未来药物设计的特定相互作用和动机.

关键词:
在FT-ICRR中.这是一个RNARNARNARNARNA.互动是一种互动.质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量小分子的小分子.

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Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...