在接受化疗的晚期癌症患者中,远程患者报告结果和步数与住院或死亡的关联:PROStep随机试验的二次分析
Christopher R Manz1, Emily Schriver2,3, William J Ferrell4,5
1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States.
Journal of medical Internet research
|May 17, 2024
概括
在晚期癌症患者中,远程监测患者报告的结果 (PRO) 和步数可以预测住院治疗或死亡. 症状增加和活动水平下降是预后不佳的关键指标.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 患者监测 患者监测
背景情况:
- 接受化疗的晚期癌症患者会出现显著的症状和功能衰退,影响结果.
- 远程监测患者报告的结果 (PROs) 和步骤计数提供了一种积极的方法来识别有风险的个体.
研究的目的:
- 评估纵向PRO和步数之间的关联.
- 评估PRO和步数与住院或死亡的关系.
主要方法:
- 该PROStep随机试验涉及108名患有晚期胃肠道或肺癌的患者.
- 这次二次分析的重点是57名干预组患者的PRO和步数数据.
- 纵向数据使用启动的通用线性模型进行了分析.
主要成果:
- 总体PRO得分增加1个点与每天步骤减少247步和住院或死亡风险增加20%相关.
- 与减少步骤相关的关键PRO包括活动,恶心和便秘.
- 减少步数 (1000步) 与16%更高的住院或死亡风险有关. 在不良事件发生前几周,步数显著下降.
结论:
- 较高的症状负担和减少的步数独立地与晚期癌症患者的不良结果有关.
- 纵向PRO和步数数据可以识别患有不良事件高风险的患者,指导有针对性的干预措施.
关键词:
加速度计的加速度计.这些都是加速仪,加速度计.癌症 癌症 癌症 癌症 癌症化学疗法 化疗 化疗死亡死亡死亡死亡死亡死亡这是胃肠道癌症.住院治疗 住院治疗肺癌是一种肺癌.手机电话 手机电话手机电话监控 监控 监控 监控 监控 监控瘤学 在瘤学方面.由患者生成的健康数据.患者报告的结果.危险的风险 危险的风险步骤计数的数量可以计数.症状负担 症状负担症状 症状 症状 症状 症状可穿戴设备可以穿戴.更多相关视频
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