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Updated: Jun 26, 2025

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
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对多域蛋白质的基本动力学和固定长度粗粒度的评估

Yu Zhu1, Xiaochuan Zhao2, Chijian Xiang3

  • 1Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.

The journal of physical chemistry. B
|May 17, 2024
PubMed
概括

固定长度粗粒度 (FLCG) 有效地模拟多域蛋白质动态,接近基本动态粗粒度 (EDCG). 这种方法简化了在多个尺度上模拟复杂的生物分子.

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