亚临床甲状腺功能障碍指南的系统审查:一系列令人惊叹的建议
Stan R Ursem1,2, Anita Boelen1,2,3, Eveline Bruinstroop4
1Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands.
European thyroid journal
|May 17, 2024
概括
亚临床甲状腺功能障碍国际指南显示,诊断测试,治疗和随访的差异很大. 需要更明确,基于证据的建议来管理这种甲状腺疾病.
科学领域:
- 内分泌学 在内分泌学.
- 临床实践指南 临床实践指南
- 系统审查是系统的审查.
背景情况:
- 亚临床甲状腺疾病管理是有争议的.
- 专注于临床意义,诊断和治疗亚临床甲状腺功能障碍症.
研究的目的:
- 系统地审查关于亚临床甲状腺功能障碍症的国际指南.
- 分析诊断工作,治疗和后续推的变化.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在PubMed,Embase和指南数据库中搜索相关的临床实践指南.
- 使用AGREE II仪器评估指南质量.
主要成果:
- 包括22条指导方针 (2007-2021年) 中等到低质量的.
- 在诊断测试中发现的实质性差异范围.
- 治疗的开始因TSH,年龄和并发症而异;随访间隔从3-12个月不等.
结论:
- 在亚临床甲状腺功能障碍国际指南中存在显著的差异.
- 需要明确,基于证据的诊断,治疗和随访建议.
- 未来的研究应该明确界定干预值.
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