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Updated: Jun 26, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Published on: May 28, 2014

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关于合成和对乙烯基驱动的Ni (II) - 二 (NNNN) 复合体对BSA/DNA结合和抗癌活性的影响的研究

Rakesh R Panicker1, Akella Sivaramakrishna1

  • 1Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore 632014, Tamil Nadu, India.

Journal of inorganic biochemistry
|May 17, 2024
PubMed
概括

新的 (II) - 二 (Ni) - 二 (II) - Tpy) 复合物显示出有希望的抗癌活性. 这些复合物表现出显著的BSA/DNA结合能力和对肺癌和乳腺癌细胞系的强有力的细胞毒性,其中一个复合物与思丁相比显示出更高的疗效.

关键词:
2,2′:6′,2′′ - - 铁皮里丁二氧化物它具有抗癌活性.DFT计算的计算方法结合DNA/BSA的结合方式(II) - - 二烯复合物结构分析 结构分析

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