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Updated: Jun 26, 2025

A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics
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A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics

Published on: September 19, 2016

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康格林素通过抑制PDGFR来抵消血管光滑肌肉细胞脱差和相关的动脉硬化

Shuang Yang1, Yixiu Zhao1, Shifeng Cao1

  • 1State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|May 17, 2024
PubMed
概括

康格莱克辛 (KLX) 通过抑制血管光滑肌细胞 (VSMC) 不分化,有效治疗动脉样硬化和动脉新极限形成. 这种新型化合物向PDGFR-β信号通路,为VSMC相关疾病提供了有前途的治疗方法.

关键词:
动脉样硬化是一种动脉样硬化.新极端的增生症.在PDGFR-β的基础上.现象型切换的切换方式在VSMC中,VSMC是VSMC.

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