辐射血流信号:甲状腺癌的一个新的超声波特征
Sha-Sha Huang1, Zheng Yang2, Bin Li3
1Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
European journal of radiology
|May 17, 2024
概括
辐射血流信号是一种新的超声波功能,可显著改善甲状腺结节的诊断. 这项新功能提高了诊断性能,与美国放射学学院甲状腺成像报告和数据系统 (ACR TI-RADS) 评分相比.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 甲状腺结节很常见,区分良性和恶性是适当管理的关键.
- 超声波 (US) 是甲状腺结节评估的主要成像方式.
- 目前的风险分层系统,如美国放射学学院甲状腺成像报告和数据系统 (ACR TI-RADS),在诊断准确性方面存在局限性.
研究的目的:
- 在超声波上总结辐射血流信号.
- 为了评估辐射血流信号在区分良性和恶性甲状腺结节的诊断价值.
- 评估将辐射血流信号与ACR TI-RADS评分相结合是否可以提高诊断性能.
主要方法:
- 从四家医院 (2018-2022) 的2475名患者的超声波数据的回顾性分析.
- 使用多变量逻辑回归来评估超声波特征与恶性瘤之间的相关性.
- 开发了结合ACR TI-RADS得分,辐射血流信号及其组合的诊断模型,并进行了内部和外部验证.
主要成果:
- 辐射血流信号被确定为甲状腺癌的独立风险因素.
- 组合模型 (辐射血流信号 + ACR TI-RADS) 在训练,内部验证和外部验证集中显示出明显更高的曲线下面积 (AUC) 值,而不是单独的ACR TI-RADS得分.
- 例如,组合模型在训练组中实现了0.95的AUC,超过了ACR TI-RADS模型 (AUC0.91).
结论:
- 辐射血流是一种与甲状腺癌相关的新型超声波特征.
- 将辐射血流信号纳入风险评估,与单独使用ACR TI-RADS评分相比,显著提高了甲状腺结节的诊断性能.
- 这一发现可以导致更准确的甲状腺结节特征和改善患者管理.
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