后COVID综合征的门诊管理 - 一个中心的经验
Fernando Torres1, Christine Shedd1, Vaidehi Kaza1
1The University of Texas Southwestern Medical Center, United States.
Heart & lung : the journal of critical care
|May 17, 2024
概括
对于COVID后间歇性肺病 (ILD) 和呼吸不良心症候群 (DTS) 的治疗,症状显著改善. 这项研究详细介绍了这些持续的COVID-19症状的管理.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 越来越多地认识到COVID-19感染后的持续症状.
- 有限的数据存在于管理长期的后COVID条件.
- 门诊对于解决COVID后的子综合征至关重要.
研究的目的:
- 描述COVID后子综合征患者的临床经验和治疗结果.
- 根据他们的症状和临床表现,识别不同的COVID后患者群体.
- 评估针对这些子综合征的特定治疗方案的有效性.
主要方法:
- 从2020年7月7日到2022年12月12日对98名COVID后患者的回顾性评估.
- 将其分为三个亚型:COVID后间歇性肺病 (ILD),呼吸障碍-心跳动综合征 (DTS) 和不分化的症状.
- 治疗包括使用类固醇,用于ILD的mycophenolate mofetil (MMF),用于DTS的metoprolol,以及对未分化组的观察.
主要成果:
- 在COVID后的ILD患者显示氧气需求减少 (1.96到0.89 L/NC,p=0.005).
- 在COVID后的DTS患者体验到静止心率下降 (98到79bpm,p=0.023).
- 在所有接受治疗的患者中,60%的人报告说有所改善的运动性呼吸障碍.
结论:
- 确定了三个不同的后COVID子综合征:ILD,DTS和不分化的症状.
- MMF和类固醇的组合有效地治疗了COVID后的ILD.
- 梅托普罗罗尔在治疗COVID后DTS症状方面是有效的.
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