相关实验视频

Updated: Jun 26, 2025

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

基于辐射皮肤炎的剂量毒性表面直方图的预测辐射皮肤炎的严重程度和形状

Chae-Seon Hong¹, Ye-In Park¹, Min-Seok Cho²

¹Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

Physics in medicine and biology

|May 17, 2024

概括

一个新的框架使用皮肤剂量分布来预测辐射性皮肤炎 (RD) 的严重程度. 这种方法可以准确预测 RD 的发生,等级和形状,帮助头癌患者的临床决策.

科学领域:

辐射瘤学辐射瘤学
医学物理医学物理
皮肤病学皮肤病学

背景情况:

放射性皮肤炎 (RD) 是放射治疗的常见副作用.
准确预测RD严重程度和位置对于患者管理至关重要.
目前用于预测RD的方法在精度和范围上是有限的.

研究的目的:

开发一种用于预测辐射性皮肤炎 (RD) 的新型框架.
利用实际RD区域内的皮肤剂量分布来根据等级确定预测剂量.
根据严重程度可视预测RD等级,发生区域和形状.

主要方法:

开发了一个框架,使用3D皮肤摄影和剂量分配来细分研发和开发领域.
剂量毒性组图 (DTHs) 是根据在细分的RD区域内皮肤剂量分布计算的.
基于DTH的预测剂量被生成并与23名头癌患者的实际RD发生率和等级进行比较.

主要成果:

基于DTH的框架成功地为RD等级1,2和3生成了DTH.
确定RD预测剂量为28.9 Gy (1级),38.1 Gy (2级) 和54.3 Gy (3级).
可视化的 RD 发生区域和形状与实际的 RD 区域呈现可接受的一致性,在大多数患者中可准确预测等级.

结论:

开发的基于DTH的框架有效地对RD严重程度进行分类,并预测其发生情况.
这种方法提供了RD区域和形状的视觉预测,帮助医生做出决策.
该框架为预测和管理患者的辐射皮肤炎提供了有价值的工具.

关键词:

剂量 - 毒性表面基因组图预测因素是一个预测因素.放射性皮肤炎是一种辐射皮肤炎.辐射治疗疗法辐射治疗疗法细分化细分化的细分化皮肤剂量皮肤剂量皮肤毒性皮肤毒性

更多相关视频

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Published on: September 4, 2017

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

相关概念视频

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Probability Histograms

Probability Histograms

A probability histogram is a visual representation of a probability distribution. Similar a typical histogram, the probability histogram consists of contiguous (adjoining) boxes. It has both a horizontal axis and a vertical axis. The horizontal axis is labeled with what the data represents. The vertical axis is labeled with probability. Each rectangular bar in the histogram is 1 unit wide, which suggests that the area under each bar equals the probability, P(x), where x is 1, 2, 3, and so on.

Histogram

Histogram

The histogram is a graphical representation in the x-y form of data distribution in a data set. The horizontal x-axis is labeled with what the data represents (for instance, distance from your home to school). The vertical y-axis is labeled either frequency or relative frequency (or percent frequency or probability).
A histogram graph consists of contiguous (adjoining) boxes. The heights of the bars correspond to frequency values. The graph will have the same shape with respective labels. The...