荷尔蒙,肝脏和功能与暴露在孟加拉国达卡的电子废物 (电子废物) 相关
Sarker Masud Parvez1, M Mamun Huda2, Mahbubur Rahman3
1Children's Health and Environment Program, Child Health Research Centre, The University of Queensland, South Brisbane, QLD 4101, Australia; Environmental Health and WASH, Health Systems and Population Studies Division, icddr,b, Dhaka 1212, Bangladesh.
电子废物 (电子废物) 回收工人暴露在 (Pb) 中显示肝脏和功能受损. 这项研究强调了电子废物暴露的健康风险,特别是污染.
科学领域:
- 环境健康 环境健康
- 职业医学 职业医学 职业医学
- 毒理学 毒理学 毒理学
背景情况:
- 电子废物 (电子废物) 含有危险金属和有机污染物.
- 电子废物回收对工人造成重大健康风险,因为潜在的暴露.
- 了解电子垃圾中特定重金属的毒理影响对于工人保护至关重要.
研究的目的:
- 调查电子废物暴露与回收工人健康结果之间的关联.
- 评估 (Pb), (Cd) 和 (Hg) 对肝脏,和激素功能的影响.
- 探索DNA氧化损伤在调解暴露相关健康影响中的作用.
主要方法:
- 使用量子回归分析来评估Pb,Cd和Hg的影响.
- 血液,尿液和头发样本被分析为重金属和生物标志物.
- 199名电子废物回收工人与104名未暴露的个人进行了比较.
主要成果:
- 暴露的工人血中 (Pb) 含量显著上升,肝酶 (AST,ALT) 和功能标志物 (尿白蛋白,ACR,eGFR) 的水平升高.
- (Pb) 暴露与性酸酶 (ALP),尿蛋白和蛋白与肌素比率 (ACR) 的增加有关.
- (Cd) 和 (Hg) 与测量的荷尔蒙,或肝脏参数没有显著的关联;DNA氧化损伤没有调解这些关系.
结论:
- 电子废物暴露,特别是 (Pb) 水平升高,在回收工人中显著损害肝脏和功能.
- 目前的调查结果强调需要持续监测和有效的控制措施来减轻健康风险.
- 建议进行进一步的纵向研究,以确定剂量反应关系和长期健康影响.
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