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相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Working Memory01:24

Working Memory

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Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
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Information Processing Approach01:30

Information Processing Approach

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The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
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The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
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相关实验视频

Updated: Jun 26, 2025

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
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将认知完整性与衰老人类大脑中的工作记忆动力学联系起来

Gina Monov1, Henrik Stein2, Leonie Klock2

  • 1Section of Computational Cognitive Neuroscience, Department of Neurophysiology & Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany monov.gina@gmail.com.

The Journal of neuroscience : the official journal of the Society for Neuroscience
|May 17, 2024
PubMed
概括

由于神经噪声增加,工作记忆随着年龄的增长而下降,影响认知功能. 这种与年龄有关的工作记忆噪音与认知完整性有关,特别是在轻度认知障碍 (MCI) 中.

关键词:
行为建模行为建模电力生理学 电力生理学神经动力学 神经动力学神经成像是一种神经成像.翻译神经科学是一种神经科学.

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科学领域:

  • 神经科学是一个神经科学.
  • 认知心理学 认知心理学
  • 衰老研究研究 衰老研究

背景情况:

  • 工作记忆 (WM) 能力随着年龄的增长而下降,影响认知表现.
  • 这种下降与刺激呈现后持续的神经活动变化有关.
  • 老年人,包括那些有轻度认知障碍 (MCI) 的人,经历WM缺陷.

研究的目的:

  • 研究工作记忆在衰老和MCI中的动态.
  • 在WM性能中区分内部噪声和决策值.
  • 将神经活动和WM的计算模型与认知完整性联系起来.

主要方法:

  • 使用行为建模,神经心理评估和磁脑电图 (MEG).
  • 参与者执行了一个视觉空间延迟匹配到样本任务.
  • 一个计算模型将内部噪声与决策值分离出来.

主要成果:

  • 随着延迟的增加和刺激的接近,任务准确性下降.
  • 老年人显示出更多的虚假警报比年轻人在小的刺激距离.
  • 计算模型显示,老年人中WM噪声增加,与MEG测量的神经活动相关.
  • 在MCI患者的内部噪音与临床认知完整性评估相关.

结论:

  • 由于神经噪声增加,工作记忆的稳定性随着年龄的增长而恶化.
  • 这种与年龄相关的WM噪声增加与MCI患者的认知完整性有关.
  • 研究结果表明神经噪声是与年龄相关的认知衰退和MCI进展的关键因素.