在妇科癌症中 Sarcopenia
Riccardo Di Fiore1, Rosa Drago-Ferrante2, Sherif Suleiman3
1Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080, Msida, Malta; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, 19122, USA.
概括
肌肉质量和功能丧失的萨尔科佩尼亚,越来越被认为是妇科癌症 (GCs) 预后不佳的重要指标. 了解其临床重要性对于改善这些疾病患者的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 病理生理学 病理生理学
背景情况:
- 妇科癌症 (GCs) 对全球死亡率构成重大挑战,通常是由于检测迟到.
- 标志着全身骨肌肉质量和功能丧失的萨尔科佩尼亚是一种多因素状况,与衰老,营养不良和包括癌症在内的慢性疾病有关.
- 由厌食症和炎症驱动的癌症缓解症加速肌肉代谢,将肉类症定位为健康状况不佳和晚期恶性瘤的标志物.
研究的目的:
- 审查被诊断患有妇科癌症的患者中肉类的临床意义.
- 突出在各种妇科恶性瘤的背景下,萨科佩尼亚的预后价值.
主要方法:
- 现有关于肉病和妇科癌症的研究的文献综述.
- 综合关于肌肉质量,功能和妇科癌症患者的结果之间的关系的证据.
主要成果:
- 越来越多的证据表明,sarcopenia是多种癌症,包括妇科癌症的显著预后因素.
- 皮症是癌症患者整体健康状况和潜在的晚期疾病的指标.
结论:
- 对于患有妇科癌症的患者来说,sarcopenia具有相当大的临床意义.
- 需要进一步的研究和多学科努力,以利用sarcopenia改进诊断,预后和治疗策略在GCs.
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