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与衰老相关的PGC-1α降低促进了疼痛慢性化

Xinbo Wu1, Liuyue Yang1, Zihua Li1

  • 1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Aging cell
|May 18, 2024
PubMed
概括

衰老会降低大脑中的PGC-1α,使老年小鼠的慢性疼痛恶化. 在主体体感官皮质 (S1) 中恢复PGC-1α可缓解这种疼痛,为老年人群的慢性疼痛提供潜在的治疗点.

关键词:
在PGC-1α中.老化的老化 衰老的老化鼠标 鼠标 鼠标 鼠标疼痛 疼痛 疼痛 疼痛人体感官皮层 (somatosensory cortex) 是一个感官皮层.

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