复发性急性髓性白血病中的切割性白血病:呼吁进行明确的分类
William J Nahm1, Michelle Juarez2, Maher Abdul-Hay3
1New York University Grossman School of Medicine, New York City, NY, USA.
The American journal of case reports
|May 18, 2024
概括
皮肤白血病 (Leukemia cutis) 是恶性髓状细胞透到皮肤的病例,在复发的急性髓状白血病中很少有报道. 这一案例表明,患有复发性急性髓性白血病和皮质白血病的患者可能有较差的结果,需要不同的分类和研究.
科学领域:
- 血液学 血液学 血液学
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 急性骨髓性白血病 (AML) 涉及骨髓前体的增殖和成熟停止.
- 皮肤白血病是恶性髓状细胞透到皮肤,其致病性不明.
- 有限的报告存在于白血病切割在复发的AML.
研究的目的:
- 在患有复发性急性髓性白血病的患者中报告白血病病例.
- 为了突出报告不足和缺乏明显分类的复发性AML与白血病切割.
- 建议对临床结果和未来研究方向的影响.
主要方法:
- 一个59岁妇女的病例报告,她有治疗过的,低风险的AML病史.
- 呈现的症状包括呼吸短促,昏迷,贫血,血小板缺血和皮下结节.
- 在复发性AML的背景下诊断白血病切皮病.
主要成果:
- 该患者出现了暗示复发AML和并发性白血病切割的症状.
- 救援化疗没有成功,患者接受了息治疗.
- 患者在诊断后一个月死亡.
结论:
- 这一案例凸显了AML复发性白血病不经常报告和缺乏区分的情况.
- 患有复发性AML和白血病切割症的患者可能与患有初级AML和白血病切割症患者相比,临床结果更差.
- 复发性AML与白血病cutis保证了将其分类为一个独特的组,用于有针对性的研究,改善后续和降低皮肤病变的活检值.
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