感染性内心炎在患有血液性恶性瘤和中性质衰竭的患者中很少见
Michael J Scolarici1, Leigh R Berman2, Natalie Callander3
1Department of Medicine, Division of Infectious Diseases, University of Wisconsin, Madison, Wisconsin, USA.
概括
感染性内心炎在患有血液恶性瘤和细菌病的中性衰竭患者中罕见. 这项研究没有发现任何病例,这表明这些高风险患者可能不需要例行心声回声扫描.
科学领域:
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 传染性内心炎 (IE) 是血液感染 (BSI) 的严重并发症.
- 血液恶性和细菌病的中性衰竭患者中IE风险的数据有限.
研究的目的:
- 评估血液恶性瘤,细菌病和中性衰竭的成年患者中IE的发病率.
- 评估回声心脏学在诊断IE在这个特定的患者群体中的实用性.
主要方法:
- 成年血液病患者 (2018-2020年) 细菌病和中性衰竭的回顾性图表审查.
- 在IE诊断中应用2023年杜克-ISCVID标准.
- 在BSI后90天的随访期间,检查新的传染性并发症.
主要成果:
- 分析了65名患有血液性恶性瘤和3级+中性质衰竭的患者的66次发作.
- 在34.8%的患者中进行过胸腔心声学 (TTE),在6.1%的患者中进行过食管心声学 (TEE).
- 没有发现感染性内心炎的病例;90天内没有发现新的感染性并发症.
结论:
- 感染性内心炎在患有血液性恶性瘤,细菌病和中性质衰竭的患者中很少见.
- 在这个队列中,常规的TTE可能是不合理的.
- 在这个人群中,TEE不太可能改善IE的以患者为中心的结果.
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