与年轻人相比,老年人≥80岁中风的病因分类:系统性审查和元分析
Johan Sanner1,2, Jakob O Ström3, Mia von Euler3
1Faculty of Medicine and Health, School of Medical Sciences, Örebro University, Örebro, Sweden.
Journal of geriatric psychiatry and neurology
|May 18, 2024
概括
老年人 (≥80岁) 与年轻人相比,心血管血栓性中风的患病率较高,小血管疾病的患病率较低. 需要进一步的研究来证实这些发现中风病因学.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 流行病学 流行病学
背景情况:
- 全球人口正在老龄化,这导致老年人中中风发病率预期增加.
- 了解中风的原因对于所有年龄组的公平医疗保健至关重要.
研究的目的:
- 系统地审查和比较80岁及以上个体与80岁以下个体中缺血性和出血性中风的病因亚型的患病率.
主要方法:
- 在主要数据库 (MEDLINE,Embase,Cochrane,Epistemonikos,Cinahl) 进行了系统的文献搜索.
- 包括比较80岁以上与80岁以下个体中风的病因分类的研究.
- 对来自8223名个人 (2997名年龄≥80岁) 的数据进行了元分析.
主要成果:
- 发现心血管血栓性中风在80岁以上 (或1.68) 个体中明显更为普遍.
- 小血管疾病在老年人群中流行率明显低 (OR 0.64).
- 在年龄组之间没有观察到大血管疾病患病率的显著差异 (OR 1.05).
结论:
- 在80岁及以上的个体中,心血管血栓性中风更常见,而小血管疾病与年轻人相比较少见.
- 由于所包含的研究数量有限,研究结果应谨慎解释.
- 建议使用经过验证的分类系统进行更大规模的研究,以确认中风中的这些病因差异.
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