患有异常性正常压力头症的老年患者的肉类:来自土耳其单一老年诊所的一项观察性研究
Ali Ekrem Aydin1, Fatma Sena Dost2, Derya Kaya3
1Department of Geriatric Medicine, School of Medicine, Ondokuz Mayis University, Samsun, Turkey.
Acta neurologica Belgica
|May 18, 2024
概括
肉症是一种肌肉损失的情况,在患有异常正常压力脑症 (iNPH) 的老年人中很常见. 这一关联强调了需要在iNPH患者中进行例行查,以管理步态和力量问题.
科学领域:
- 老年病的医生 老年病的医生
- 神经学 神经学
- 物理疗法物理治疗
背景情况:
- 异常性正常压力脑症 (iNPH) 是一种神经退行性疾病,影响着步态,认知和膀控制,在老年人群中越来越普遍.
- 标志着肌肉力量和质量减少的萨科佩尼亚显著导致步行困难,并且在老年人中更为普遍.
- 存在潜在的双向关系,iNPH通过步行障碍和减少体力活动加剧了萨科佩尼亚,而萨科佩尼亚可能会影响iNPH的进展.
研究的目的:
- 在老龄化的人群中,研究骨症和异常性正常压力头症 (iNPH) 之间的关联.
- 为了确定与对照组相比,在被诊断为iNPH的患者中发生的肉类的患病率.
- 为了确定与iNPH患者的萨尔科佩尼亚相关的临床因素.
主要方法:
- 这是一项追溯的横截面研究,涉及327名参与者,其中51名是iNPH和276名对照.
- 收集的数据包括人口统计,并发症,药物,跌倒史,实验室结果和综合老年评估 (CGA) 参数.
- 使用欧洲老年人肉症工作组2 (EWGSOP2) 标准诊断了肉症,并使用回归分析来评估肉症和iNPH之间的关系.
主要成果:
- 与对照组相比,iNPH组 (19.6%) 的麻症患病率明显高于对照组 (2.5%) (p < 0.01).
- 在调整了混杂因素后,iNPH患者的可能缩症的几率是3.89倍,缓慢步行速度的几率是8.47倍.
- 在iNPH患者中,较低的迷你精神状态检查得分与可能的肉相关 (OR = 0.869,p = 0.042).
结论:
- 麻症是老年人与异常性正常压力头症 (iNPH) 的常见并发症.
- 这些发现表明,在iNPH患者中,肉类,肌肉强度下降和步行速度减慢之间存在强烈的关联.
- 建议医生对老年iNPH患者进行例行评估,以解决潜在的不良影响并改善结果.
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