人体血液中的微塑料:使用μFTIRIR的聚合物类型,度和表征
Sophie V L Leonard1, Catriona R Liddle1, Charlotte A Atherall1
1Centre for Biomedicine, Hull York Medical School, University of Hull, Kingston-upon-Hull, HU6 7RX, United Kingdom.
Environment international
|May 18, 2024
概括
微塑料 (MPs) 存在于人体血液中,在90%的捐赠者中检测到24种聚合物类型. 这些微小的塑料颗粒,主要是碎片,引起了人们对潜在的健康影响的担忧,例如血管炎症和器官积累.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 人类健康 人类健康 人类健康
背景情况:
- 微塑料 (MP) 是普遍存在的环境污染物.
- 已在各种环境矩阵中检测到MPs,并且越来越多地在人体内发现.
- 人类血液中MPs的存在和特征需要进一步调查.
研究的目的:
- 识别和量化人类全血中MPs的类型,大小和形状.
- 评估健康志愿者的血液样本中的MPs度.
- 探索与流通中的MP存在相关的潜在健康影响.
主要方法:
- 分析了来自20名健康捐献者的全人血液样本.
- 使用先进的分析技术识别和量化MP聚合物类型.
- MP粒子的大小,形状和颜色的表征.
主要成果:
- 在90%的捐赠者中发现了24种聚合物类型;五种聚合物类型超过了量化极限 (LOQ).
- MP度在1.84 - 4.65微克/毫升之间,其中聚乙烯,乙烯基二烯和乙烯基乙烯酸/酒精是最丰富的.
- 主要情况下,MP是碎片 (88%),白色/透明 (79%),尺寸从7-3000微米长5-800微米宽. 还检测到塑料添加剂,包括酸盐.
结论:
- 这项研究证实了MPs在人体血液中的吸收和循环.
- 检测到的MP的特征表明血管炎症,器官积累以及免疫和静血功能变化的潜在风险.
- 进一步的研究对于了解MP暴露的长期健康后果至关重要.
相关概念视频
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