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Updated: Jun 26, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

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作为抗癌剂的可离子和不可离子带的双核形环

A van Niekerk1, S Chakraborty2, C Bellis2

  • 1Department of Chemistry and Polymer Science, Stellenbosch University, Private bag X1, Stellenbosch 7602, South Africa,; Department of Human Biology, University of Cape Town, Private Bag X3, Rondebosch 7701, South Africa.

Journal of inorganic biochemistry
|May 18, 2024
PubMed
概括

这项研究比较了新型的Palladacycle抗癌药物,发现PEGylated化合物对乳腺癌细胞有效. 一种类型显示毒性降低和选择性提高,为基治疗提供了有前途的替代方案.

关键词:
这是一种抗癌药物.BSA 有约束性的 BSA 有约束性的结合 DNA 的 DNA 结合.分子建模分子建模通过PEGylation进行化.托盘式自行车是什么意思

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